Adenosine and inosine release during hypoxia in the isolated spinal cord of rats Running title: Adenosine and inosine release during hypoxia
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Title Adenosine and inosine release during hypoxia in the isolated spinal cord of neonatal rats Author(s) Takahashi, T.; Otsuguro, K.; Ohta, T.; Ito, S. Citation British Journal of Pharmacology, 161(8): 1806-1816 Issue Date 2010-12 Doc URL http://hdl.handle.net/2115/47528 Right The definitive version is available at www.interscience.wiley.com Type article (author version) File Information BJP161-8_1806-1816.pdf
منابع مشابه
Differential contributions of adenosine to hypoxia-evoked depressions of three neuronal pathways in isolated spinal cord of neonatal rats.
BACKGROUND AND PURPOSE Hypoxic effects on neuronal functions vary significantly with experimental conditions, but the mechanism for this is unclear. Adenosine has been reported to play a key role in depression of neuronal activities in the CNS during acute hypoxia. Hence, we examined the effect of acute hypoxia on different spinal reflex potentials and the contribution of adenosine to them. E...
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BERNE, ROBERT h/l. Cardiac nucleotides in hypoxia: possible role . . in regulation of coronary blood flow. Am. J. Physiol. 204(2) : 317-322. I 963 .-Experiments were performed on isolated cat hearts perfused with Tyrode’s solution and intact hearts of open-chest dogs. Cardiac hypoxia resulted in a decrease in coronary vascular resistance and a release of significant amounts of inosine and hypox...
متن کامل5'-Nucleotidase activity and adenosine formation in stimulated, hypoxic and underperfused rat heart.
Changes in 5'-nucleotidase activity were calculated on the basis of alterations in ATP, ADP, phosphocreatine, Pi, Mg2+, IMP and AMP, determined by using 31P n.m.r. spectroscopy and h.p.l.c., during isoprenaline infusion, graded hypoxia and graded underperfusion in isolated rat heart. Calculated activity changes were compared with the total efflux of purines (adenosine + inosine + hypoxanthine) ...
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تاریخ انتشار 2017